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CD40-Activated B Cells Can Efficiently Prime Antigen-Specific Naïve CD8(+) T Cells to Generate Effector but Not Memory T cells

BACKGROUND: The identification of the signals that should be provided by antigen-presenting cells (APCs) to induce a CD8(+) T cell response in vivo is essential to improve vaccination strategies using antigen-loaded APCs. Although dendritic cells have been extensively studied, the ability of other A...

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Detalles Bibliográficos
Autores principales: Mathieu, Mélissa, Cotta-Grand, Natacha, Daudelin, Jean-François, Boulet, Salix, Lapointe, Réjean, Labrecque, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264565/
https://www.ncbi.nlm.nih.gov/pubmed/22291907
http://dx.doi.org/10.1371/journal.pone.0030139