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Arousal of Cancer-Associated Stroma: Overexpression of Palladin Activates Fibroblasts to Promote Tumor Invasion

BACKGROUND: Cancer-associated fibroblasts, comprised of activated fibroblasts or myofibroblasts, are found in the stroma surrounding solid tumors. These myofibroblasts promote invasion and metastasis of cancer cells. Mechanisms regulating the activation of the fibroblasts and the initiation of invas...

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Detalles Bibliográficos
Autores principales: Brentnall, Teresa A., Lai, Lisa A., Coleman, Joshua, Bronner, Mary P., Pan, Sheng, Chen, Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264580/
https://www.ncbi.nlm.nih.gov/pubmed/22291919
http://dx.doi.org/10.1371/journal.pone.0030219

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