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LPS Regulates SOCS2 Transcription in a Type I Interferon Dependent Autocrine-Paracrine Loop

Recent studies suggest that SOCS2 is involved in the regulation of TLR signaling. In this study, we found that the expression of SOCS2 is regulated in human monocyte-derived DC by ligands stimulating TLR2, 3, 4, 5, 8 and 9 signaling. SOCS2 induction by LPS was dependent on the type I IFN regulated t...

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Detalles Bibliográficos
Autores principales:	Hu, Jin, Lou, DaoHua, Carow, Berit, Winerdal, Malin E., Rottenberg, Martin, Wikström, Ann-Charlotte, Norstedt, Gunnar, Winqvist, Ola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264591/ https://www.ncbi.nlm.nih.gov/pubmed/22291912 http://dx.doi.org/10.1371/journal.pone.0030166

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