Downregulation of RKIP Is Associated with Poor Outcome and Malignant Progression in Gliomas

Malignant gliomas are highly infiltrative and invasive tumors, which precludes the few treatment options available. Therefore, there is an urgent need to elucidate the molecular mechanisms underlying gliomas aggressive phenotype and poor prognosis. The Raf Kinase Inhibitory protein (RKIP), besides r...

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Detalles Bibliográficos
Autores principales: Martinho, Olga, Granja, Sara, Jaraquemada, Teresa, Caeiro, Cláudia, Miranda-Gonçalves, Vera, Honavar, Mrinalini, Costa, Paulo, Damasceno, Margarida, Rosner, Marsha R., Lopes, José M., Reis, Rui M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264629/
https://www.ncbi.nlm.nih.gov/pubmed/22292035
http://dx.doi.org/10.1371/journal.pone.0030769

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