Cargando…
Physicochemical and Biological Evaluation of siRNA Polyplexes Based on PEGylated Poly(amido amine)s
PURPOSE: Use of RNA interference as novel therapeutic strategy is hampered by inefficient delivery of its mediator, siRNA, to target cells. Cationic polymers have been thoroughly investigated for this purpose but often display unfavorable characteristics for systemic administration, such as interact...
Autores principales: | Vader, Pieter, van der Aa, Leonardus J., Engbersen, Johan F. J., Storm, Gert, Schiffelers, Raymond M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264854/ https://www.ncbi.nlm.nih.gov/pubmed/21833793 http://dx.doi.org/10.1007/s11095-011-0545-z |
Ejemplares similares
-
Disulfide-Based Poly(amido amine)s for siRNA Delivery: Effects of Structure on siRNA Complexation, Cellular Uptake, Gene Silencing and Toxicity
por: Vader, Pieter, et al.
Publicado: (2010) -
Targeted Delivery of siRNA
por: Oliveira, Sabrina, et al.
Publicado: (2006) -
Synthetic poly(ester amine) and poly(amido amine) nanoparticles for efficient DNA and siRNA delivery to human endothelial cells
por: Tzeng, Stephany Y, et al.
Publicado: (2011) -
Multilayered Thin Films from Boronic Acid-Functional Poly(amido amine)s
por: Hujaya, Sry D., et al.
Publicado: (2015) -
Multilayered Thin Films from Boronic Acid-Functional Poly(amido amine)s As Drug-Releasing Surfaces
por: Hujaya, Sry D., et al.
Publicado: (2015)