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Accurate microRNA Target Prediction Using Detailed Binding Site Accessibility and Machine Learning on Proteomics Data

MicroRNAs (miRNAs) are a class of small regulatory genes regulating gene expression by targeting messenger RNA. Though computational methods for miRNA target prediction are the prevailing means to analyze their function, they still miss a large fraction of the targeted genes and additionally predict...

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Detalles Bibliográficos
Autores principales: Reczko, Martin, Maragkakis, Manolis, Alexiou, Panagiotis, Papadopoulos, Giorgio L., Hatzigeorgiou, Artemis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265086/
https://www.ncbi.nlm.nih.gov/pubmed/22303397
http://dx.doi.org/10.3389/fgene.2011.00103

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