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Accurate microRNA Target Prediction Using Detailed Binding Site Accessibility and Machine Learning on Proteomics Data
MicroRNAs (miRNAs) are a class of small regulatory genes regulating gene expression by targeting messenger RNA. Though computational methods for miRNA target prediction are the prevailing means to analyze their function, they still miss a large fraction of the targeted genes and additionally predict...
Autores principales: | Reczko, Martin, Maragkakis, Manolis, Alexiou, Panagiotis, Papadopoulos, Giorgio L., Hatzigeorgiou, Artemis G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265086/ https://www.ncbi.nlm.nih.gov/pubmed/22303397 http://dx.doi.org/10.3389/fgene.2011.00103 |
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