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Lack of Intestinal Epithelial Atg7 Affects Paneth Cell Granule Formation but Does Not Compromise Immune Homeostasis in the Gut

Genetic polymorphisms of autophagy-related genes have been associated with an increased risk to develop inflammatory bowel disease (IBD). Autophagy is an elementary process participating in several cellular events such as cellular clearance and nonapoptotic programmed cell death. Furthermore, autoph...

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Detalles Bibliográficos
Autores principales: Wittkopf, Nadine, Günther, Claudia, Martini, Eva, Waldner, Maximilian, Amann, Kerstin U., Neurath, Markus F., Becker, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265132/
https://www.ncbi.nlm.nih.gov/pubmed/22291845
http://dx.doi.org/10.1155/2012/278059