Cargando…

Intraosseous Synovial Sarcoma of the Proximal Tibia

Synovial Sarcoma is a malignant mesenchymal tumor that comprises 5–10% of all soft tissue sarcomas. The mean age of onset is thirty years old. Intraosseous presentation is very rare and has only been documented a few times. We report herein a case of a 53-year-old man with synovial sarcoma arising i...

Descripción completa

Detalles Bibliográficos
Autores principales: Beck, Sarah E., Nielsen, G. Petur, Raskin, Kevin A., Schwab, Joseph H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265277/
https://www.ncbi.nlm.nih.gov/pubmed/22312495
http://dx.doi.org/10.1155/2011/184891
_version_ 1782222064031105024
author Beck, Sarah E.
Nielsen, G. Petur
Raskin, Kevin A.
Schwab, Joseph H.
author_facet Beck, Sarah E.
Nielsen, G. Petur
Raskin, Kevin A.
Schwab, Joseph H.
author_sort Beck, Sarah E.
collection PubMed
description Synovial Sarcoma is a malignant mesenchymal tumor that comprises 5–10% of all soft tissue sarcomas. The mean age of onset is thirty years old. Intraosseous presentation is very rare and has only been documented a few times. We report herein a case of a 53-year-old man with synovial sarcoma arising in the left proximal tibia. The patient underwent a wide surgical resection and reconstruction, followed by adjuvant chemotherapy. Three years later, the patient developed a local recurrence that resulted in an above-the-knee amputation. Eight months later, the patient has completed chemotherapy and is without signs of recurrence. The current recommended treatment for synovial sarcoma is wide surgical resection followed by chemotherapy as well as long-term followup. Despite improved surgical techniques, long-term survival rates remain low.
format Online
Article
Text
id pubmed-3265277
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-32652772012-02-06 Intraosseous Synovial Sarcoma of the Proximal Tibia Beck, Sarah E. Nielsen, G. Petur Raskin, Kevin A. Schwab, Joseph H. Int J Surg Oncol Case Report Synovial Sarcoma is a malignant mesenchymal tumor that comprises 5–10% of all soft tissue sarcomas. The mean age of onset is thirty years old. Intraosseous presentation is very rare and has only been documented a few times. We report herein a case of a 53-year-old man with synovial sarcoma arising in the left proximal tibia. The patient underwent a wide surgical resection and reconstruction, followed by adjuvant chemotherapy. Three years later, the patient developed a local recurrence that resulted in an above-the-knee amputation. Eight months later, the patient has completed chemotherapy and is without signs of recurrence. The current recommended treatment for synovial sarcoma is wide surgical resection followed by chemotherapy as well as long-term followup. Despite improved surgical techniques, long-term survival rates remain low. Hindawi Publishing Corporation 2011 2011-05-14 /pmc/articles/PMC3265277/ /pubmed/22312495 http://dx.doi.org/10.1155/2011/184891 Text en Copyright © 2011 Sarah E. Beck et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Beck, Sarah E.
Nielsen, G. Petur
Raskin, Kevin A.
Schwab, Joseph H.
Intraosseous Synovial Sarcoma of the Proximal Tibia
title Intraosseous Synovial Sarcoma of the Proximal Tibia
title_full Intraosseous Synovial Sarcoma of the Proximal Tibia
title_fullStr Intraosseous Synovial Sarcoma of the Proximal Tibia
title_full_unstemmed Intraosseous Synovial Sarcoma of the Proximal Tibia
title_short Intraosseous Synovial Sarcoma of the Proximal Tibia
title_sort intraosseous synovial sarcoma of the proximal tibia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265277/
https://www.ncbi.nlm.nih.gov/pubmed/22312495
http://dx.doi.org/10.1155/2011/184891
work_keys_str_mv AT becksarahe intraosseoussynovialsarcomaoftheproximaltibia
AT nielsengpetur intraosseoussynovialsarcomaoftheproximaltibia
AT raskinkevina intraosseoussynovialsarcomaoftheproximaltibia
AT schwabjosephh intraosseoussynovialsarcomaoftheproximaltibia