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Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients

Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients w...

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Autores principales: Delviks-Frankenberry, Krista A., Chaipan, Chawaree, Bagni, Rachel, Wyvill, Kathleen, Yarchoan, Robert, Pathak, Vinay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265315/
https://www.ncbi.nlm.nih.gov/pubmed/22312354
http://dx.doi.org/10.1155/2011/797820
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author Delviks-Frankenberry, Krista A.
Chaipan, Chawaree
Bagni, Rachel
Wyvill, Kathleen
Yarchoan, Robert
Pathak, Vinay K.
author_facet Delviks-Frankenberry, Krista A.
Chaipan, Chawaree
Bagni, Rachel
Wyvill, Kathleen
Yarchoan, Robert
Pathak, Vinay K.
author_sort Delviks-Frankenberry, Krista A.
collection PubMed
description Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients with HIV-associated lymphomas are infected with XMRV. Analysis of PMBCs and plasma from 26 patients failed to detect XMRV by PCR, ELISA, or Western blot, suggesting a lack of association between XMRV and AIDS-associated lymphomas.
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spelling pubmed-32653152012-02-06 Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients Delviks-Frankenberry, Krista A. Chaipan, Chawaree Bagni, Rachel Wyvill, Kathleen Yarchoan, Robert Pathak, Vinay K. Adv Virol Research Article Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients with HIV-associated lymphomas are infected with XMRV. Analysis of PMBCs and plasma from 26 patients failed to detect XMRV by PCR, ELISA, or Western blot, suggesting a lack of association between XMRV and AIDS-associated lymphomas. Hindawi Publishing Corporation 2011 2011-09-08 /pmc/articles/PMC3265315/ /pubmed/22312354 http://dx.doi.org/10.1155/2011/797820 Text en Copyright © 2011 Krista A. Delviks-Frankenberry et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Delviks-Frankenberry, Krista A.
Chaipan, Chawaree
Bagni, Rachel
Wyvill, Kathleen
Yarchoan, Robert
Pathak, Vinay K.
Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
title Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
title_full Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
title_fullStr Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
title_full_unstemmed Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
title_short Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
title_sort lack of detection of xenotropic murine leukemia virus-related virus in hiv-1 lymphoma patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265315/
https://www.ncbi.nlm.nih.gov/pubmed/22312354
http://dx.doi.org/10.1155/2011/797820
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