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Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265315/ https://www.ncbi.nlm.nih.gov/pubmed/22312354 http://dx.doi.org/10.1155/2011/797820 |
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author | Delviks-Frankenberry, Krista A. Chaipan, Chawaree Bagni, Rachel Wyvill, Kathleen Yarchoan, Robert Pathak, Vinay K. |
author_facet | Delviks-Frankenberry, Krista A. Chaipan, Chawaree Bagni, Rachel Wyvill, Kathleen Yarchoan, Robert Pathak, Vinay K. |
author_sort | Delviks-Frankenberry, Krista A. |
collection | PubMed |
description | Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients with HIV-associated lymphomas are infected with XMRV. Analysis of PMBCs and plasma from 26 patients failed to detect XMRV by PCR, ELISA, or Western blot, suggesting a lack of association between XMRV and AIDS-associated lymphomas. |
format | Online Article Text |
id | pubmed-3265315 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-32653152012-02-06 Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients Delviks-Frankenberry, Krista A. Chaipan, Chawaree Bagni, Rachel Wyvill, Kathleen Yarchoan, Robert Pathak, Vinay K. Adv Virol Research Article Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-infection, we asked whether certain patients with HIV-associated lymphomas are infected with XMRV. Analysis of PMBCs and plasma from 26 patients failed to detect XMRV by PCR, ELISA, or Western blot, suggesting a lack of association between XMRV and AIDS-associated lymphomas. Hindawi Publishing Corporation 2011 2011-09-08 /pmc/articles/PMC3265315/ /pubmed/22312354 http://dx.doi.org/10.1155/2011/797820 Text en Copyright © 2011 Krista A. Delviks-Frankenberry et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Delviks-Frankenberry, Krista A. Chaipan, Chawaree Bagni, Rachel Wyvill, Kathleen Yarchoan, Robert Pathak, Vinay K. Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
title | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
title_full | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
title_fullStr | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
title_full_unstemmed | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
title_short | Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients |
title_sort | lack of detection of xenotropic murine leukemia virus-related virus in hiv-1 lymphoma patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265315/ https://www.ncbi.nlm.nih.gov/pubmed/22312354 http://dx.doi.org/10.1155/2011/797820 |
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