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Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

A major barrier to research on Parkinson's disease is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells from patients and differentiate them into neurons affected by disease. Triplication of SNCA, encoding α-synuclein, causes a fully penetran...

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Detalles Bibliográficos
Autores principales:	Devine, Michael J., Ryten, Mina, Vodicka, Petr, Thomson, Alison J., Burdon, Tom, Houlden, Henry, Cavaleri, Fatima, Nagano, Masumi, Drummond, Nicola J., Taanman, Jan-Willem, Schapira, Anthony H., Gwinn, Katrina, Hardy, John, Lewis, Patrick A., Kunath, Tilo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265381/ https://www.ncbi.nlm.nih.gov/pubmed/21863007 http://dx.doi.org/10.1038/ncomms1453

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