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Editing of human K(V)1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity
In the nervous system, A→I RNA editing has an important role in regulating neuronal excitability. Ligand-gated membrane receptors, synaptic proteins, as well as ion channels, are targets for recoding by RNA editing. Although scores of editing sites have been identified in the mammalian brain, little...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Pub. Group
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265383/ https://www.ncbi.nlm.nih.gov/pubmed/21847110 http://dx.doi.org/10.1038/ncomms1446 |