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Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure

BACKGROUND: Fe(3)O(4)-gold-chitosan core-shell nanostructure can be used in biotechnological and biomedical applications such as magnetic bioseparation, water and wastewater treatment, biodetection and bioimaging, drug delivery, and cancer treatment. RESULTS: Magnetite nanoparticles with an average...

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Autores principales: Salehizadeh, Hossein, Hekmatian, Elham, Sadeghi, Meisam, Kennedy, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265409/
https://www.ncbi.nlm.nih.gov/pubmed/22221555
http://dx.doi.org/10.1186/1477-3155-10-3
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author Salehizadeh, Hossein
Hekmatian, Elham
Sadeghi, Meisam
Kennedy, Kevin
author_facet Salehizadeh, Hossein
Hekmatian, Elham
Sadeghi, Meisam
Kennedy, Kevin
author_sort Salehizadeh, Hossein
collection PubMed
description BACKGROUND: Fe(3)O(4)-gold-chitosan core-shell nanostructure can be used in biotechnological and biomedical applications such as magnetic bioseparation, water and wastewater treatment, biodetection and bioimaging, drug delivery, and cancer treatment. RESULTS: Magnetite nanoparticles with an average size of 9.8 nm in diameter were synthesized using the chemical co-precipitation method. A gold-coated Fe(3)O(4 )monotonous core-shell nanostructure was produced with an average size of 15 nm in diameter by glucose reduction of Au(3+ )which is then stabilized with a chitosan cross linked by formaldehyde. The results of analyses with X-ray diffraction (XRD), Fourier Transformed Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), and Atomic Force Microscopy (AFM) indicated that the nanoparticles were regularly shaped, and agglomerate-free, with a narrow size distribution. CONCLUSIONS: A rapid, mild method for synthesizing Fe(3)O(4)-gold nanoparticles using chitosan was investigated. A magnetic core-shell-chitosan nanocomposite, including both the supermagnetic properties of iron oxide and the optical characteristics of colloidal gold nanoparticles, was synthesized.
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spelling pubmed-32654092012-01-25 Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure Salehizadeh, Hossein Hekmatian, Elham Sadeghi, Meisam Kennedy, Kevin J Nanobiotechnology Research BACKGROUND: Fe(3)O(4)-gold-chitosan core-shell nanostructure can be used in biotechnological and biomedical applications such as magnetic bioseparation, water and wastewater treatment, biodetection and bioimaging, drug delivery, and cancer treatment. RESULTS: Magnetite nanoparticles with an average size of 9.8 nm in diameter were synthesized using the chemical co-precipitation method. A gold-coated Fe(3)O(4 )monotonous core-shell nanostructure was produced with an average size of 15 nm in diameter by glucose reduction of Au(3+ )which is then stabilized with a chitosan cross linked by formaldehyde. The results of analyses with X-ray diffraction (XRD), Fourier Transformed Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), and Atomic Force Microscopy (AFM) indicated that the nanoparticles were regularly shaped, and agglomerate-free, with a narrow size distribution. CONCLUSIONS: A rapid, mild method for synthesizing Fe(3)O(4)-gold nanoparticles using chitosan was investigated. A magnetic core-shell-chitosan nanocomposite, including both the supermagnetic properties of iron oxide and the optical characteristics of colloidal gold nanoparticles, was synthesized. BioMed Central 2012-01-05 /pmc/articles/PMC3265409/ /pubmed/22221555 http://dx.doi.org/10.1186/1477-3155-10-3 Text en Copyright ©2012 Salehizadeh et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Salehizadeh, Hossein
Hekmatian, Elham
Sadeghi, Meisam
Kennedy, Kevin
Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure
title Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure
title_full Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure
title_fullStr Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure
title_full_unstemmed Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure
title_short Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure
title_sort synthesis and characterization of core-shell fe(3)o(4)-gold-chitosan nanostructure
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265409/
https://www.ncbi.nlm.nih.gov/pubmed/22221555
http://dx.doi.org/10.1186/1477-3155-10-3
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