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Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure
BACKGROUND: Fe(3)O(4)-gold-chitosan core-shell nanostructure can be used in biotechnological and biomedical applications such as magnetic bioseparation, water and wastewater treatment, biodetection and bioimaging, drug delivery, and cancer treatment. RESULTS: Magnetite nanoparticles with an average...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265409/ https://www.ncbi.nlm.nih.gov/pubmed/22221555 http://dx.doi.org/10.1186/1477-3155-10-3 |
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author | Salehizadeh, Hossein Hekmatian, Elham Sadeghi, Meisam Kennedy, Kevin |
author_facet | Salehizadeh, Hossein Hekmatian, Elham Sadeghi, Meisam Kennedy, Kevin |
author_sort | Salehizadeh, Hossein |
collection | PubMed |
description | BACKGROUND: Fe(3)O(4)-gold-chitosan core-shell nanostructure can be used in biotechnological and biomedical applications such as magnetic bioseparation, water and wastewater treatment, biodetection and bioimaging, drug delivery, and cancer treatment. RESULTS: Magnetite nanoparticles with an average size of 9.8 nm in diameter were synthesized using the chemical co-precipitation method. A gold-coated Fe(3)O(4 )monotonous core-shell nanostructure was produced with an average size of 15 nm in diameter by glucose reduction of Au(3+ )which is then stabilized with a chitosan cross linked by formaldehyde. The results of analyses with X-ray diffraction (XRD), Fourier Transformed Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), and Atomic Force Microscopy (AFM) indicated that the nanoparticles were regularly shaped, and agglomerate-free, with a narrow size distribution. CONCLUSIONS: A rapid, mild method for synthesizing Fe(3)O(4)-gold nanoparticles using chitosan was investigated. A magnetic core-shell-chitosan nanocomposite, including both the supermagnetic properties of iron oxide and the optical characteristics of colloidal gold nanoparticles, was synthesized. |
format | Online Article Text |
id | pubmed-3265409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-32654092012-01-25 Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure Salehizadeh, Hossein Hekmatian, Elham Sadeghi, Meisam Kennedy, Kevin J Nanobiotechnology Research BACKGROUND: Fe(3)O(4)-gold-chitosan core-shell nanostructure can be used in biotechnological and biomedical applications such as magnetic bioseparation, water and wastewater treatment, biodetection and bioimaging, drug delivery, and cancer treatment. RESULTS: Magnetite nanoparticles with an average size of 9.8 nm in diameter were synthesized using the chemical co-precipitation method. A gold-coated Fe(3)O(4 )monotonous core-shell nanostructure was produced with an average size of 15 nm in diameter by glucose reduction of Au(3+ )which is then stabilized with a chitosan cross linked by formaldehyde. The results of analyses with X-ray diffraction (XRD), Fourier Transformed Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), and Atomic Force Microscopy (AFM) indicated that the nanoparticles were regularly shaped, and agglomerate-free, with a narrow size distribution. CONCLUSIONS: A rapid, mild method for synthesizing Fe(3)O(4)-gold nanoparticles using chitosan was investigated. A magnetic core-shell-chitosan nanocomposite, including both the supermagnetic properties of iron oxide and the optical characteristics of colloidal gold nanoparticles, was synthesized. BioMed Central 2012-01-05 /pmc/articles/PMC3265409/ /pubmed/22221555 http://dx.doi.org/10.1186/1477-3155-10-3 Text en Copyright ©2012 Salehizadeh et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Salehizadeh, Hossein Hekmatian, Elham Sadeghi, Meisam Kennedy, Kevin Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure |
title | Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure |
title_full | Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure |
title_fullStr | Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure |
title_full_unstemmed | Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure |
title_short | Synthesis and characterization of core-shell Fe(3)O(4)-gold-chitosan nanostructure |
title_sort | synthesis and characterization of core-shell fe(3)o(4)-gold-chitosan nanostructure |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265409/ https://www.ncbi.nlm.nih.gov/pubmed/22221555 http://dx.doi.org/10.1186/1477-3155-10-3 |
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