Cargando…

Interferon-Alpha Administration Enhances CD8+ T Cell Activation in HIV Infection

BACKGROUND: Type I interferons play important roles in innate immune defense. In HIV infection, type I interferons may delay disease progression by inhibiting viral replication while at the same time accelerating disease progression by contributing to chronic immune activation. METHODS: To investiga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Manion, Maura, Rodriguez, Benigno, Medvik, Kathleen, Hardy, Gareth, Harding, Clifford V., Schooley, Robert T., Pollard, Richard, Asmuth, David, Murphy, Robert, Barker, Edward, Brady, Kirsten E., Landay, Alan, Funderburg, Nick, Sieg, Scott F., Lederman, Michael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265460/ https://www.ncbi.nlm.nih.gov/pubmed/22291932 http://dx.doi.org/10.1371/journal.pone.0030306

Ejemplares similares

Interferon-α Is the Primary Plasma Type-I IFN in HIV-1 Infection and Correlates with Immune Activation and Disease Markers
por: Hardy, Gareth A. D., et al.
Publicado: (2013)

Toll-Like Receptor Ligands Induce Human T Cell Activation and Death, a Model for HIV Pathogenesis
por: Funderburg, Nicholas, et al.
Publicado: (2008)

Decreased IL-7 Responsiveness Is Related to Oxidative Stress in HIV Disease
por: Kalinowska, Magdalina, et al.
Publicado: (2013)

Characteristics and Outcomes of Initial Virologic Suppressors during Analytic Treatment Interruption in a Therapeutic HIV-1 gag Vaccine Trial
por: Li, Jonathan Z., et al.
Publicado: (2012)

Interferon Alpha Association with Neuromyelitis Optica
por: Asgari, Nasrin, et al.
Publicado: (2013)

Altered Monocyte Phenotype in HIV-1 Infection Tends to Normalize with Integrase-Inhibitor-Based Antiretroviral Therapy
por: McCausland, Marie R., et al.
Publicado: (2015)

Poxviral Targeting of Interferon Regulatory Factor Activation
por: Lawler, Clara, et al.
Publicado: (2020)

Synergistic inhibition of human cytomegalovirus replication by interferon-alpha/beta and interferon-gamma
por: Sainz, Bruno, et al.
Publicado: (2005)

Interferons Alpha, Beta, and Omega
por: Meager, Anthony
Publicado: (1998)

Prospective Analysis of Lipid Composition Changes with Antiretroviral Therapy and Immune Activation in Persons Living with HIV
por: Belury, Martha A., et al.
Publicado: (2017)

Successful treatment of psychosis induced by interferon alpha and ribavirin with paliperidone: first case reported
por: Carrillo de Albornoz Calahorro, Carmen Maura, et al.
Publicado: (2019)

Strain-specific responsiveness of hepatitis D virus to interferon-alpha treatment
por: Giersch, Katja, et al.
Publicado: (2023)

Interferon Alpha Induces Establishment of Alphaherpesvirus Latency in Sensory Neurons In Vitro
por: De Regge, Nick, et al.
Publicado: (2010)

Interferon Alpha in Systemic Lupus Erythematosus
por: Niewold, Timothy B., et al.
Publicado: (2010)

Shared and Unique Features of Human Interferon-Beta and Interferon-Alpha Subtypes
por: Wittling, Megen C., et al.
Publicado: (2021)

Altered Monocyte and Endothelial Cell Adhesion Molecule Expression Is Linked to Vascular Inflammation in Human Immunodeficiency Virus Infection
por: Kulkarni, Manjusha, et al.
Publicado: (2016)

Stability of plasma indices of inflammation/coagulation and homeostasis after fatty and non-fatty meals in treated people with HIV
por: Dorazio, Dominic, et al.
Publicado: (2019)

Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta
Publicado: (1988)

Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells
Publicado: (1993)

Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent
por: Hillyer, Philippa, et al.
Publicado: (2012)

Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent
por: Hillyer, P, et al.
Publicado: (2013)

Comparative effectiveness and safety of ribavirin plus interferon-alpha, lopinavir/ritonavir plus interferon-alpha, and ribavirin plus lopinavir/ritonavir plus interferon-alpha in patients with mild to moderate novel coronavirus disease 2019: study protocol
por: Zeng, Yan-Ming, et al.
Publicado: (2020)

Altered Lipidome Composition Is Related to Markers of Monocyte and Immune Activation in Antiretroviral Therapy Treated Human Immunodeficiency Virus (HIV) Infection and in Uninfected Persons
por: Bowman, Emily R., et al.
Publicado: (2019)

The Interferon Response Dampens the Usutu Virus Infection-Associated Increase in Glycolysis
por: Wald, Maria Elisabeth, et al.
Publicado: (2022)

Inflammatory signaling compromises cell responses to interferon alpha
por: HuangFu, Wei-Chun, et al.
Publicado: (2011)

Successful Treatment of Provisional Cutaneous Mastocytosis with Interferon Alpha
por: Rosario, Andrea, et al.
Publicado: (2016)

Cloning, expression and antiviral activity of mink alpha-interferons
por: Zhang, Hai-ling, et al.
Publicado: (2015)

Different Biological Activities of Specific Interferon Alpha Subtypes
por: Hasenkrug, Kim J., et al.
Publicado: (2019)

Intraventricular recombinant alpha-interferon in subacute sclerosing panencephalitis
por: Cianchetti, C., et al.
Publicado: (1991)

Studies on the suitability of alpha-hybrid interferon application in cattle
por: Straub, Otto Christian
Publicado: (1995)

Positive Selection of the Bat Interferon Alpha Gene Family
por: He, Guimei, et al.
Publicado: (2010)

Heritability of alpha and sensorimotor network changes in temporal lobe epilepsy
por: Yaakub, Siti N., et al.
Publicado: (2020)

Exosomal Interferon‐Induced Transmembrane Protein 2 Transmitted to Dendritic Cells Inhibits Interferon Alpha Pathway Activation and Blocks Anti–Hepatitis B Virus Efficacy of Exogenous Interferon Alpha
por: Shi, Ying, et al.
Publicado: (2019)

Interferon-alpha is a predisposing risk factor for carbamazepine-induced hyponatremia: A case of syndrome of inappropriate antidiuresis caused by interferon-alpha therapy
por: Tanaka, Midori, et al.
Publicado: (2009)

Antitumor effect of an adeno-associated virus expressing apolipoprotein A-1 fused to interferon alpha in an interferon alpha-resistant murine tumor model
por: Vasquez, Marcos, et al.
Publicado: (2016)

Effect of a genetically engineered interferon-alpha versus traditional interferon-alpha in the treatment of moderate-to-severe COVID-19: a randomised clinical trial
por: Li, Chuan, et al.
Publicado: (2021)

Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice
por: van de Garde, Martijn D. B., et al.
Publicado: (2017)

Pharmacokinetic Characteristics, Pharmacodynamic Effect and In Vivo Antiviral Efficacy of Liver-Targeted Interferon Alpha
por: Rycroft, Daniel, et al.
Publicado: (2015)

Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors
Publicado: (1995)

Exacerbation of hepatitis C induced subclinical hypoadrenalism by Interferon-alpha2beta: A case report
por: Tran, Huy A, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_umiu4utbpeu0j36lp909lrbjck