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QSAR studies on a number of pyrrolidin-2-one antiarrhythmic arylpiperazinyls
The activity of a number of 1-[3-(4-arylpiperazin-1-yl)propyl]pyrrolidin-2-one antiarrhythmic (AA) agents was described using the quantitative structure–activity relationship model by applying it to 33 compounds. The molecular descriptors of the AA activity were obtained by quantum chemical calculat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer-Verlag
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265727/ https://www.ncbi.nlm.nih.gov/pubmed/22308062 http://dx.doi.org/10.1007/s00044-010-9540-x |