Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restoration

Cognitive dysfunctions are common in major depressive disorder, but have been difficult to recapitulate in animal models. This study shows that Flinders sensitive line (FSL) rats, a genetic rat model of depression, display a pronounced impairment of emotional memory function in the passive avoidance...

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Detalles Bibliográficos
Autores principales: Eriksson, T M, Delagrange, P, Spedding, M, Popoli, M, Mathé, A A, Ögren, S O, Svenningsson, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265836/
https://www.ncbi.nlm.nih.gov/pubmed/21242991
http://dx.doi.org/10.1038/mp.2010.131

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