Cargando…

The Ras protein superfamily: Evolutionary tree and role of conserved amino acids

Mostrar otras versiones (1)

The Ras superfamily is a fascinating example of functional diversification in the context of a preserved structural framework and a prototypic GTP binding site. Thanks to the availability of complete genome sequences of species representing important evolutionary branch points, we have analyzed the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rojas, Ana Maria, Fuentes, Gloria, Rausell, Antonio, Valencia, Alfonso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265948/ https://www.ncbi.nlm.nih.gov/pubmed/22270915 http://dx.doi.org/10.1083/jcb.201103008

Ejemplares similares

The Ras protein superfamily: Evolutionary tree and role of conserved amino acids
por: Rojas, Ana Maria, et al.
Publicado: (2012)

Conserved amino acid networks modulate discrete functional properties in an enzyme superfamily
por: Narayanan, Chitra, et al.
Publicado: (2017)

Functional Roles of the Conserved Amino Acid Sequence Motif C, the Antiporter Motif, in Membrane Transporters of the Major Facilitator Superfamily
por: Varela, Manuel F., et al.
Publicado: (2023)

The Eps1p Protein Disulfide Isomerase Conserves Classic Thioredoxin Superfamily Amino Acid Motifs but Not Their Functional Geometries
por: Biran, Shai, et al.
Publicado: (2014)

Evolution and Diversity of the Ras Superfamily of Small GTPases in Prokaryotes
por: Wuichet, Kristin, et al.
Publicado: (2014)

Emerging RAS superfamily conditions involving GTPase function
por: Shieh, Joseph T. C.
Publicado: (2019)

ERAS, a Member of the Ras Superfamily, Acts as an Oncoprotein in the Mammary Gland
por: Suarez-Cabrera, Cristian, et al.
Publicado: (2021)

The evolution of the Puf superfamily of proteins across the tree of eukaryotes
por: Najdrová, Vladimíra, et al.
Publicado: (2020)

Prioritization of pathogenic mutations in the protein kinase superfamily
por: Izarzugaza, Jose MG, et al.
Publicado: (2012)

Evolutionary history of the TBP-domain superfamily
por: Brindefalk, Björn, et al.
Publicado: (2013)

The Ras Superfamily of Small GTPases in Non-neoplastic Cerebral Diseases
por: Qu, Liang, et al.
Publicado: (2019)

SCOPmap: Automated assignment of protein structures to evolutionary superfamilies
por: Cheek, Sara, et al.
Publicado: (2004)

Regulation of p53 oligomerization by Ras superfamily protein RBEL1A
por: Lui, Ki, et al.
Publicado: (2015)

Genome Wide Analysis of Amino Acid Transporter Superfamily in Solanum lycopersicum
por: Omari Alzahrani, Fatima
Publicado: (2021)

Structural and evolutionary bioinformatics of the SPOUT superfamily of methyltransferases
por: Tkaczuk, Karolina L, et al.
Publicado: (2007)

Evolutionary History of the Photolyase/Cryptochrome Superfamily in Eukaryotes
por: Mei, Qiming, et al.
Publicado: (2015)

The amino acid sequences of the myelin-associated glycoproteins: homology to the immunoglobulin gene superfamily
Publicado: (1987)

Properties of the Thioredoxin Fold Superfamily Are Modulated by a Single Amino Acid Residue
por: Ren, Guoping, et al.
Publicado: (2009)

Resculpting the binding pocket of APC superfamily LeuT-fold amino acid transporters
por: Edwards, Noel, et al.
Publicado: (2017)

Metazoan Remaining Genes for Essential Amino Acid Biosynthesis: Sequence Conservation and Evolutionary Analyses
por: Costa, Igor R., et al.
Publicado: (2014)

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
por: Commisso, Cosimo, et al.
Publicado: (2013)

Lysine-acetylation as a fundamental regulator of Ran function: Implications for signaling of proteins of the Ras-superfamily
por: Knyphausen, Philipp, et al.
Publicado: (2015)

Evolutionary and functional relationships within the DJ1 superfamily
por: Bandyopadhyay, Sourav, et al.
Publicado: (2004)

Phylogenomic evolutionary surveys of subtilase superfamily genes in fungi
por: Li, Juan, et al.
Publicado: (2017)

The Identification and Evolutionary Trends of the Solute Carrier Superfamily in Arthropods
por: Denecke, Shane M, et al.
Publicado: (2020)

Relative Stabilities of Conserved and Non-Conserved Structures in the OB-Fold Superfamily
por: Guardino, Kaitlyn M., et al.
Publicado: (2009)

Wavelet coherence phase analysis decodes the universal switching mechanism of Ras GTPase superfamily
por: Motiwala, Zenia, et al.
Publicado: (2023)

The WD-repeat protein superfamily in Arabidopsis: conservation and divergence in structure and function
por: van Nocker, Steven, et al.
Publicado: (2003)

Evolutionary history and stress regulation of the lectin superfamily in higher plants
por: Jiang, Shu-Ye, et al.
Publicado: (2010)

Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily
por: Akiva, Eyal, et al.
Publicado: (2017)

Evolutionary Pattern of N-Glycosylation Sequon Numbers in Eukaryotic ABC Protein Superfamilies
por: Rao, R. Shyama Prasad, et al.
Publicado: (2010)

Structural updates of alignment of protein domains and consequences on evolutionary models of domain superfamilies
por: Mutt, Eshita, et al.
Publicado: (2013)

Repurposing conformational changes in ANL superfamily enzymes to rapidly generate biosensors for organic and amino acids
por: Wang, Jin, et al.
Publicado: (2023)

On the evolutionary conservation of hydrogen bonds made by buried polar amino acids: the hidden joists, braces and trusses of protein architecture
por: Worth, Catherine L, et al.
Publicado: (2010)

Mutational Studies on Resurrected Ancestral Proteins Reveal Conservation of Site-Specific Amino Acid Preferences throughout Evolutionary History
por: Risso, Valeria A., et al.
Publicado: (2015)

Molecular evolution and functional divergence of tubulin superfamily in the fungal tree of life
por: Zhao, Zhongtao, et al.
Publicado: (2014)

Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily
por: Jackson, Brian C, et al.
Publicado: (2011)

Optogenetic modulation of guanine nucleotide exchange factors of Ras superfamily proteins directly controls cell shape and movement
por: Pal, Dhiman Sankar, et al.
Publicado: (2023)

Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression
por: Perland, Emelie, et al.
Publicado: (2017)

Evolutionarily Conserved Substrate Substructures for Automated Annotation of Enzyme Superfamilies
por: Chiang, Ranyee A., et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_hcn4rht1m3qj3egj3hequnuf5p