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FAK and talin: Who is taking whom to the integrin engagement party?

In this issue, Lawson et al. provide new insight into the relationship between FAK and talin during assembly of integrin adhesions on fibronectin. They show that FAK is upstream of talin, and that talin is not required for FAK recruitment or for integrin activation at nascent adhesions. However, FAK...

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Detalles Bibliográficos
Autores principales: Serrels, Bryan, Frame, Margaret C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265951/
https://www.ncbi.nlm.nih.gov/pubmed/22270914
http://dx.doi.org/10.1083/jcb.201112128

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