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Long-Range Modulation of Chain Motions within the Intrinsically Disordered Transactivation Domain of Tumor Suppressor p53

[Image: see text] The tumor suppressor p53 is a hub protein with a multitude of binding partners, many of which target its intrinsically disordered N-terminal domain, p53-TAD. Partners, such as the N-terminal domain of MDM2, induce formation of local structure and leave the remainder of the domain a...

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Detalles Bibliográficos
Autores principales:	Lum, Jenifer K., Neuweiler, Hannes, Fersht, Alan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2011
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265989/ https://www.ncbi.nlm.nih.gov/pubmed/22176582 http://dx.doi.org/10.1021/ja2078619

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