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Gelatinase-stimuli strategy enhances the tumor delivery and therapeutic efficacy of docetaxel-loaded poly(ethylene glycol)-poly(ɛ-caprolactone) nanoparticles

Nanoscale drug carriers have been extensively developed to improve drug therapeutic efficiency. However, delivery of chemotherapeutic agents to tumor tissues and cells has not been favorably managed. In this study, we developed a novel “intelligent” nanoparticle, consisting of a gelatinase-cleavage...

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Detalles Bibliográficos
Autores principales: Liu, Qin, Li, Ru-Tian, Qian, Han-Qing, Yang, Mi, Zhu, Zhen-Shu, Wu, Wei, Qian, Xiao-Ping, Yu, Li-Xia, Jiang, Xi-Qun, Liu, Bao-Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265997/
https://www.ncbi.nlm.nih.gov/pubmed/22287839
http://dx.doi.org/10.2147/IJN.S26697