Cargando…

A potential role of the JNK pathway in hyperoxia-induced cell death, myofibroblast transdifferentiation and TGF-β1-mediated injury in the developing murine lung

BACKGROUND: Transforming growth factor-beta 1 (TGF-β1) has been implicated in hyperoxia-induced cell death and impaired alveolarization in the developing lung. In addition, the c-JunNH2-terminal kinase (JNK) pathway has been shown to have a role for TGF-β1-mediated effects. We hypothesized that the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zhang, Choo-Wing, Rayman, Sun, Huanxing, Sureshbabu, Angara, Sakurai, Reiko, Rehan, Virender K, Bhandari, Vineet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266206/ https://www.ncbi.nlm.nih.gov/pubmed/22172122 http://dx.doi.org/10.1186/1471-2121-12-54

Ejemplares similares

A Critical Regulatory Role for Macrophage Migration Inhibitory Factor in Hyperoxia-Induced Injury in the Developing Murine Lung
por: Sun, Huanxing, et al.
Publicado: (2013)

Small molecular modulation of macrophage migration inhibitory factor in the hyperoxia-induced mouse model of bronchopulmonary dysplasia
por: Sun, Huanxing, et al.
Publicado: (2013)

Targeting mitochondrial dysfunction in lung diseases: emphasis on mitophagy
por: Sureshbabu, Angara, et al.
Publicado: (2013)

Nintedanib inhibits TGF-β-induced myofibroblast transdifferentiation in human Tenon’s fibroblasts
por: Lin, Xianchai, et al.
Publicado: (2018)

Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung
por: Sureshbabu, Angara, et al.
Publicado: (2015)

TGF-β-induced interleukin-6 participates in transdifferentiation of human Tenon’s fibroblasts to myofibroblasts
por: Seong, Gong Je, et al.
Publicado: (2009)

The Role of Focal Adhesion Kinase in the TGF-β-Induced Myofibroblast Transdifferentiation of Human Tenon's Fibroblasts
por: Hong, Samin, et al.
Publicado: (2012)

MEK inhibition prevents TGF-β1-induced myofibroblast transdifferentiation in human tenon fibroblasts
por: Wen, Jiamin, et al.
Publicado: (2019)

Telomere dysfunction promotes transdifferentiation of human fibroblasts into myofibroblasts
por: Razdan, Neetu, et al.
Publicado: (2018)

The signal pathway for the repressive effect of dipyridamole on myofibroblast transdifferentiation
por: Yan, Qiong, et al.
Publicado: (2018)

Zebularine suppresses TGF-beta-induced lens epithelial cell–myofibroblast transdifferentiation by inhibiting MeCP2
por: Zhou, Peng, et al.
Publicado: (2011)

Lefty-1 alleviates TGF-β1-induced fibroblast–myofibroblast transdifferentiation in NRK-49F cells
por: Zhang, Lijun, et al.
Publicado: (2015)

miR-216a exacerbates TGF-β-induced myofibroblast transdifferentiation via PTEN/AKT signaling
por: Qu, Chuan, et al.
Publicado: (2019)

AR12286 Alleviates TGF-β-Related Myofibroblast Transdifferentiation and Reduces Fibrosis after Glaucoma Filtration Surgery
por: Cheng, Wen-Sheng, et al.
Publicado: (2020)

JNK and p38 Inhibitors Prevent Transforming Growth Factor-β1-Induced Myofibroblast Transdifferentiation in Human Graves’ Orbital Fibroblasts
por: Hou, Tzu-Yu, et al.
Publicado: (2021)

Inflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2016)

Effects of cyclosporin, nifedipine and phenytoin on gingival myofibroblast transdifferentiation in monkeys
por: Kanno, Claudia Misue, et al.
Publicado: (2018)

Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models
por: Yao, Qin, et al.
Publicado: (2009)

Role of Nitric Oxide Isoforms in Vascular and Alveolar Development and Lung Injury in Vascular Endothelial Growth Factor Overexpressing Neonatal Mice Lungs
por: Syed, Mansoor A., et al.
Publicado: (2016)

Inhibition of miR-29 by TGF-beta-Smad3 Signaling through Dual Mechanisms Promotes Transdifferentiation of Mouse Myoblasts into Myofibroblasts
por: Zhou, Liang, et al.
Publicado: (2012)

Retraction: Blockage of transdifferentiation from fibroblast to myofibroblast in experimental ovarian cancer models
por: Yao, Qin, et al.
Publicado: (2009)

Swimming Exercise Prevents Fibrogenesis in Chronic Kidney Disease by Inhibiting the Myofibroblast Transdifferentiation
por: Peng, Chiung-Chi, et al.
Publicado: (2012)

Role of Heat Shock Protein 47 in Transdifferentiation of Human Tenon's Fibroblasts to Myofibroblasts
por: Hong, Samin, et al.
Publicado: (2012)

GED-0507 attenuates lung fibrosis by counteracting myofibroblast transdifferentiation in vivo and in vitro
por: Speca, Silvia, et al.
Publicado: (2021)

Myofibroblast transdifferentiation is associated with changes in cellular and extracellular vesicle miRNA abundance
por: Zainal Abidin, Siti Amalina Inche, et al.
Publicado: (2021)

Myofibroblast transdifferentiation of keratocytes results in slower migration and lower sensitivity to mesoscale curvatures
por: van der Putten, Cas, et al.
Publicado: (2022)

SARA suppresses myofibroblast precursor transdifferentiation in fibrogenesis in a mouse model of scleroderma
por: Corano Scheri, Katia, et al.
Publicado: (2022)

Coordinate activities of BRD4 and CDK9 in the transcriptional elongation complex are required for TGFβ-induced Nox4 expression and myofibroblast transdifferentiation
por: Ijaz, Talha, et al.
Publicado: (2017)

Histone Methyltransferase ASH1 Orchestrates Fibrogenic Gene Transcription During Myofibroblast Transdifferentiation
por: Perugorria, Maria Jesus, et al.
Publicado: (2012)

YAP activation promotes the transdifferentiation of cardiac fibroblasts to myofibroblasts in matrix remodeling of dilated cardiomyopathy
por: Jin, Bo, et al.
Publicado: (2018)

Vincristine Promotes Transdifferentiation of Fibroblasts Into Myofibroblasts via P38 and ERK Signal Pathways
por: Xu, Hui, et al.
Publicado: (2022)

Selective Inhibition of Bromodomain-Containing Protein 4 Reduces Myofibroblast Transdifferentiation and Pulmonary Fibrosis
por: Bernau, Ksenija, et al.
Publicado: (2022)

Role of Secretoglobin(+) (club cell) NFκB/RelA-TGFβ signaling in aero-allergen-induced epithelial plasticity and subepithelial myofibroblast transdifferentiation
por: Skibba, Melissa E., et al.
Publicado: (2021)

Electrical Stimulation Promotes Wound Healing by Enhancing Dermal Fibroblast Activity and Promoting Myofibroblast Transdifferentiation
por: Rouabhia, Mahmoud, et al.
Publicado: (2013)

Arecoline-induced myofibroblast transdifferentiation from human buccal mucosal fibroblasts is mediated by ZEB1
por: Chang, Yu-Chao, et al.
Publicado: (2014)

Oxidative stress induces monocyte‐to‐myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma
por: Huang, Xin, et al.
Publicado: (2020)

Transient Receptor Potential Channel Canonical Type 3 Deficiency Antagonizes Myofibroblast Transdifferentiation In Vivo
por: Xia, Weijie, et al.
Publicado: (2020)

Hyperoxia inhibits alveolar epithelial repair by inhibiting the transdifferentiation of alveolar epithelial type II cells into type I cells
por: McKechnie, S, et al.
Publicado: (2008)

Essential role of connective tissue growth factor (CTGF) in transforming growth factor-β1 (TGF-β1)-induced myofibroblast transdifferentiation from Graves’ orbital fibroblasts
por: Tsai, Chieh-Chih, et al.
Publicado: (2018)

Effects of Hyperoxia on the Refraction in Murine Neonatal and Adult Models
por: Mori, Kiwako, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qhdd1fgblrgs9oj5h7mdn24r5g