Genetic Profiling Using Genome-Wide Significant Coronary Artery Disease Risk Variants Does Not Improve the Prediction of Subclinical Atherosclerosis: The Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey – A Meta-Analysis of Three Independent Studies

BACKGROUND: Genome-wide association studies (GWASs) have identified a large number of variants (SNPs) associating with an increased risk of coronary artery disease (CAD). Recently, the CARDIoGRAM consortium published a GWAS based on the largest study population so far. They successfully replicated t...

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Detalles Bibliográficos
Autores principales: Hernesniemi, Jussi A., Seppälä, Ilkka, Lyytikäinen, Leo-Pekka, Mononen, Nina, Oksala, Niku, Hutri-Kähönen, Nina, Juonala, Markus, Taittonen, Leena, Smith, Erin N., Schork, Nicholas J., Chen, Wei, Srinivasan, Sathanur R., Berenson, Gerald S., Murray, Sarah S., Laitinen, Tomi, Jula, Antti, Kettunen, Johannes, Ripatti, Samuli, Laaksonen, Reijo, Viikari, Jorma, Kähönen, Mika, Raitakari, Olli T., Lehtimäki, Terho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266236/
https://www.ncbi.nlm.nih.gov/pubmed/22295058
http://dx.doi.org/10.1371/journal.pone.0028931

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