TLR2/MyD88/NF-κB Pathway, Reactive Oxygen Species, Potassium Efflux Activates NLRP3/ASC Inflammasome during Respiratory Syncytial Virus Infection

Human respiratory syncytial virus (RSV) constitute highly pathogenic virus that cause severe respiratory diseases in newborn, children, elderly and immuno-compromised individuals. Airway inflammation is a critical regulator of disease outcome in RSV infected hosts. Although “controlled” inflammation...

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Detalles Bibliográficos
Autores principales: Segovia, Jesus, Sabbah, Ahmed, Mgbemena, Victoria, Tsai, Su-Yu, Chang, Te-Hung, Berton, Michael T., Morris, Ian R., Allen, Irving C., Ting, Jenny P.-Y., Bose, Santanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266238/
https://www.ncbi.nlm.nih.gov/pubmed/22295065
http://dx.doi.org/10.1371/journal.pone.0029695

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