Fetal and Neonatal Goiter in Cynomolgus Monkeys Following Administration of the Antithyroid Drug Thiamazole at High Doses to Dams During Pregnancy

To evaluate morphologic alterations in the thyroid gland in the second generation in cynomolgus monkeys, pregnant dams were exposed to high doses of thiamazole. In Experiment A, dams received thiamazole intragastrically via a nasogastric catheter from gestation day (GD) 50 to GD 150 or on the day be...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Tsuyoshi, Moriyama, Akiko, Kodama, Rinya, Sasaki, Yuji, Sunagawa, Tatsumi, Okazaki, Takanobu, Urashima, Asami, Nishida, Yoshiro, Arima, Akihiro, Inoue, Ayumi, Negishi, Takayuki, Yoshikawa, Yasuhiro, Ihara, Toshio, Maeda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Toxicologic Pathology 2011
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266356/
https://www.ncbi.nlm.nih.gov/pubmed/22319233
http://dx.doi.org/10.1293/tox.24.215

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