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Activation of Endoplasmic Reticulum Stress by Hyperglycemia Is Essential for Müller Cell–Derived Inflammatory Cytokine Production in Diabetes

Inflammation plays an important role in diabetes-induced retinal vascular leakage. The purpose of this study is to examine the role of endoplasmic reticulum (ER) stress and the signaling pathway of ER stress–induced activating transcription factor 4 (ATF4) in the regulation of Müller cell–derived in...

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Detalles Bibliográficos
Autores principales: Zhong, Yimin, Li, Jingming, Chen, Yanming, Wang, Joshua J., Ratan, Rajiv, Zhang, Sarah X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266398/
https://www.ncbi.nlm.nih.gov/pubmed/22228718
http://dx.doi.org/10.2337/db11-0315