Heritable Transmission of Diabetic Metabolic Memory in Zebrafish Correlates With DNA Hypomethylation and Aberrant Gene Expression

Metabolic memory (MM) is the phenomenon whereby diabetes complications persist and progress after glycemic recovery is achieved. Here, we present data showing that MM is heritable and that the transmission correlates with hyperglycemia-induced DNA hypomethylation and aberrant gene expression. Strept...

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Detalles Bibliográficos
Autores principales: Olsen, Ansgar S., Sarras, Michael P., Leontovich, Alexey, Intine, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266410/
https://www.ncbi.nlm.nih.gov/pubmed/22228713
http://dx.doi.org/10.2337/db11-0588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266410/
https://www.ncbi.nlm.nih.gov/pubmed/22228713
http://dx.doi.org/10.2337/db11-0588

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