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Transglutaminase 2 is secreted from smooth muscle cells by transamidation-dependent microparticle formation
Transglutaminase 2 (TG2) is a pleiotropic enzyme involved in both intra- and extracellular processes. In the extracellular matrix, TG2 stabilizes the matrix by both covalent cross-linking and disulfide isomerase activity. These functions become especially apparent during matrix remodeling as seen in...
Autores principales: | van den Akker, Jeroen, van Weert, Angela, Afink, Gijs, Bakker, Erik N. T. P., van der Pol, Edwin, Böing, Anita N., Nieuwland, Rienk, VanBavel, Ed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266506/ https://www.ncbi.nlm.nih.gov/pubmed/21830119 http://dx.doi.org/10.1007/s00726-011-1010-3 |
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