The O-mannosylation and production of recombinant APA (45/47 KDa) protein from Mycobacterium tuberculosis in Streptomyces lividans is affected by culture conditions in shake flasks

BACKGROUND: The Ala-Pro-rich O-glycoprotein known as the 45/47 kDa or APA antigen from Mycobacterium tuberculosis is an immunodominant adhesin restricted to mycobacterium genus and has been proposed as an alternative candidate to generate a new vaccine against tuberculosis or for diagnosis kits. In...

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Detalles Bibliográficos
Autores principales: Gamboa-Suasnavart , Ramsés A, Valdez-Cruz, Norma A, Cordova-Dávalos, Laura E, Martínez-Sotelo , José A, Servín-González, Luis, Espitia, Clara, Trujillo-Roldán , Mauricio A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266650/
https://www.ncbi.nlm.nih.gov/pubmed/22185589
http://dx.doi.org/10.1186/1475-2859-10-110

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