THE CRYSTAL STRUCTURE OF A VOLTAGE-GATED SODIUM CHANNEL

Voltage-gated sodium channels initiate electrical signaling in excitable cells and are the molecular targets for drugs and disease mutations, but the structural basis for their voltage-dependent activation, ion selectivity, and drug block is unknown. Here, we report the crystal structure of a voltag...

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Detalles Bibliográficos
Autores principales: Payandeh, Jian, Scheuer, Todd, Zheng, Ning, Catterall, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266868/
https://www.ncbi.nlm.nih.gov/pubmed/21743477
http://dx.doi.org/10.1038/nature10238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266868/
https://www.ncbi.nlm.nih.gov/pubmed/21743477
http://dx.doi.org/10.1038/nature10238

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