High-Density SNP Mapping of the HLA Region Identifies Multiple Independent Susceptibility Loci Associated with Selective IgA Deficiency

Selective IgA deficiency (IgAD; serum IgA<0.07 g/l) is the most common form of human primary immune deficiency, affecting approximately 1∶600 individuals in populations of Northern European ancestry. The polygenic nature of IgAD is underscored by the recent identification of several new risk gene...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferreira, Ricardo C., Pan-Hammarström, Qiang, Graham, Robert R., Fontán, Gumersindo, Lee, Annette T., Ortmann, Ward, Wang, Ning, Urcelay, Elena, Fernández-Arquero, Miguel, Núñez, Concepción, Jorgensen, Gudmundur, Ludviksson, Björn R., Koskinen, Sinikka, Haimila, Katri, Padyukov, Leonid, Gregersen, Peter K., Hammarström, Lennart, Behrens, Timothy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266887/
https://www.ncbi.nlm.nih.gov/pubmed/22291608
http://dx.doi.org/10.1371/journal.pgen.1002476

Ejemplares similares

Ejemplares similares