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Biochemical Discrimination between Selenium and Sulfur 2: Mechanistic Investigation of the Selenium Specificity of Human Selenocysteine Lyase

Selenium is an essential trace element incorporated into selenoproteins as selenocysteine. Selenocysteine (Sec) lyases (SCLs) and cysteine (Cys) desulfurases (CDs) catalyze the removal of selenium or sulfur from Sec or Cys, respectively, and generally accept both substrates. Intriguingly, human SCL...

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Detalles Bibliográficos
Autores principales:	Johansson, Ann-Louise, Collins, Ruairi, Arnér, Elias S. J., Brzezinski, Peter, Högbom, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266904/ https://www.ncbi.nlm.nih.gov/pubmed/22291978 http://dx.doi.org/10.1371/journal.pone.0030528

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