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Role of Mitofusin 2 in the Renal Stress Response

The role of mitofusin 2 (MFN2), a key regulator of mitochondrial morphology and function in the renal stress response is unknown. To assess its role, the MFN2 floxed gene was conditionally deleted in the kidney of mice (MFN2 cKO) by Pax2 promoter driven Cre expression (Pax2Cre). MFN2 cKO caused seve...

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Detalles Bibliográficos
Autores principales:	Gall, Jonathan M., Wang, Zhiyong, Liesa, Marc, Molina, Anthony, Havasi, Andrea, Schwartz, John H., Shirihai, Orian, Borkan, Steven C., Bonegio, Ramon G. B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266928/ https://www.ncbi.nlm.nih.gov/pubmed/22292091 http://dx.doi.org/10.1371/journal.pone.0031074

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