The Intracellular DNA Sensor IFI16 Gene Acts as Restriction Factor for Human Cytomegalovirus Replication

Human interferon (IFN)-inducible IFI16 protein, an innate immune sensor of intracellular DNA, modulates various cell functions, however, its role in regulating virus growth remains unresolved. Here, we adopt two approaches to investigate whether IFI16 exerts pro- and/or anti-viral actions. First, th...

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Detalles Bibliográficos
Autores principales: Gariano, Grazia Rosaria, Dell'Oste, Valentina, Bronzini, Matteo, Gatti, Deborah, Luganini, Anna, De Andrea, Marco, Gribaudo, Giorgio, Gariglio, Marisa, Landolfo, Santo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266931/
https://www.ncbi.nlm.nih.gov/pubmed/22291595
http://dx.doi.org/10.1371/journal.ppat.1002498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266931/
https://www.ncbi.nlm.nih.gov/pubmed/22291595
http://dx.doi.org/10.1371/journal.ppat.1002498

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