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Systems Biology Approaches Reveal a Specific Interferon-Inducible Signature in HTLV-1 Associated Myelopathy
Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that persists lifelong in the host. In ∼4% of infected people, HTLV-1 causes a chronic disabling neuroinflammatory disease known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The pathogenesis of HAM/TSP is unknown a...
Autores principales: | Tattermusch, Sonja, Skinner, Jason A., Chaussabel, Damien, Banchereau, Jacques, Berry, Matthew P., McNab, Finlay W., O'Garra, Anne, Taylor, Graham P., Bangham, Charles R. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266939/ https://www.ncbi.nlm.nih.gov/pubmed/22291590 http://dx.doi.org/10.1371/journal.ppat.1002480 |
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