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Systems Biology Approaches Reveal a Specific Interferon-Inducible Signature in HTLV-1 Associated Myelopathy

Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that persists lifelong in the host. In ∼4% of infected people, HTLV-1 causes a chronic disabling neuroinflammatory disease known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The pathogenesis of HAM/TSP is unknown a...

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Detalles Bibliográficos
Autores principales: Tattermusch, Sonja, Skinner, Jason A., Chaussabel, Damien, Banchereau, Jacques, Berry, Matthew P., McNab, Finlay W., O'Garra, Anne, Taylor, Graham P., Bangham, Charles R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266939/
https://www.ncbi.nlm.nih.gov/pubmed/22291590
http://dx.doi.org/10.1371/journal.ppat.1002480

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