Functional analysis of missense variants in the TRESK (KCNK18) K(+) channel

A loss of function mutation in the TRESK K2P potassium channel (KCNK18), has recently been linked with typical familial migraine with aura. We now report the functional characterisation of additional TRESK channel missense variants identified in unrelated patients. Several variants either had no app...

Descripción completa

Detalles Bibliográficos
Autores principales: Andres-Enguix, Isabelle, Shang, Lijun, Stansfeld, Phillip J., Morahan, Julia M., Sansom, Mark S. P., Lafrenière, Ronald G., Roy, Bishakha, Griffiths, Lyn R., Rouleau, Guy A., Ebers, George C., Cader, Zameel M., Tucker, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266952/
https://www.ncbi.nlm.nih.gov/pubmed/22355750
http://dx.doi.org/10.1038/srep00237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266952/
https://www.ncbi.nlm.nih.gov/pubmed/22355750
http://dx.doi.org/10.1038/srep00237

Ejemplares similares