Cargando…

Midkine: A Promising Molecule for Drug Development to Treat Diseases of the Central Nervous System

Midkine (MK) is a heparin-binding cytokine, and promotes growth, survival, migration and other activities of target cells. After describing the general properties of MK, this review focuses on MK and MK inhibitors as therapeutics for diseases in the central nervous system. MK is strongly expressed d...

Descripción completa

Detalles Bibliográficos
Autor principal:	Muramatsu, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers Ltd 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267162/ https://www.ncbi.nlm.nih.gov/pubmed/21375488 http://dx.doi.org/10.2174/138161211795164167

Ejemplares similares

Midkine in Inflammation
por: Weckbach, Ludwig T., et al.
Publicado: (2011)

Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases
por: Muramatsu, Takashi
Publicado: (2010)

Midkine in repair of the injured nervous system
por: Yoshida, Yoshihiro, et al.
Publicado: (2014)

The promise of exosome applications in treating central nervous system diseases
por: Mattingly, Jared, et al.
Publicado: (2021)

Increased Midkine Gene Expression in Human Gastrointestinal Cancers
por: Aridome, Kuniaki, et al.
Publicado: (1995)

Midkine inhibitors: application of a simple assay procedure to screening of inhibitory compounds
por: Matsui, Takashi, et al.
Publicado: (2010)

Midkine induces the transformation of NIH3T3 cells.
por: Kadomatsu, K., et al.
Publicado: (1997)

Delivering the Promise of Gene Therapy with Nanomedicines in Treating Central Nervous System Diseases
por: Luo, Meihua, et al.
Publicado: (2022)

Serum midkine levels are increased in patients with various types of carcinomas
por: Ikematsu, S, et al.
Publicado: (2000)

Midkine as a factor to counteract the deposition of amyloid β-peptide plaques: in vitro analysis and examination in knockout mice
por: Muramatsu1, Hisako, et al.
Publicado: (2011)

Involvement of midkine in the development of pulmonary fibrosis
por: Misa, Kenichi, et al.
Publicado: (2017)

Promising Nanotechnology Approaches in Treatment of Autoimmune Diseases of Central Nervous System
por: Chountoulesi, Maria, et al.
Publicado: (2020)

Repulsive Guidance Molecule-a and Central Nervous System Diseases
por: Tang, Jinhua, et al.
Publicado: (2021)

Expression of midkine in the early stage of carcinogenesis in human colorectal cancer
por: Ye, C, et al.
Publicado: (1999)

Truncated midkine as a marker of diagnosis and detection of nodal metastases in gastrointestinal carcinomas.
por: Aridome, K., et al.
Publicado: (1998)

Systemic and Local Drug Delivery for Treating Diseases of the Central Nervous System in Rodent Models
por: Serwer, Laura, et al.
Publicado: (2010)

Serum Midkine Levels in Systemic Lupus Erythematosus
por: Marpaung, Blondina, et al.
Publicado: (2018)

Peripheral nervous system: A promising source of neuronal progenitors for central nervous system repair
por: Mueller, Jessica L., et al.
Publicado: (2022)

Correlation of elevated level of blood midkine with poor prognostic factors of human neuroblastomas
por: Ikematsu, S, et al.
Publicado: (2003)

Midkine—A novel player in cardiovascular diseases
por: Majaj, Marina, et al.
Publicado: (2022)

Midkine: The Who, What, Where, and When of a Promising Neurotrophic Therapy for Perinatal Brain Injury
por: Ross-Munro, Emily, et al.
Publicado: (2020)

Central nervous system biomarkers for antiobesity drug development()
por: Ziauddeen, Hisham, et al.
Publicado: (2013)

Midkine’s Role in Cardiac Pathology
por: Woulfe, Kathleen C., et al.
Publicado: (2017)

Antifungal Drugs: Special Problems Treating Central Nervous System Infections
por: Ashley, Elizabeth Dodds
Publicado: (2019)

Midkine promoter-based conditionally replicative adenovirus therapy for midkine-expressing human pancreatic cancer
por: Toyoda, Eiji, et al.
Publicado: (2008)

Chondroitin sulfates and their binding molecules in the central nervous system
por: Djerbal, L, et al.
Publicado: (2017)

Target Molecules of STIM Proteins in the Central Nervous System
por: Serwach, Karolina, et al.
Publicado: (2020)

Inhibition of the Growth Factor MDK/Midkine by a Novel Small Molecule Compound to Treat Non-Small Cell Lung Cancer
por: Hao, Huifang, et al.
Publicado: (2013)

Transcranial low-intensity ultrasound stimulation for treating central nervous system disorders: A promising therapeutic application
por: Hu, Yun-Yun, et al.
Publicado: (2023)

Leptin sustains spontaneous remyelination in the adult central nervous system
por: Matoba, Ken, et al.
Publicado: (2017)

Delivery of Therapeutic Agents to the Central Nervous System and the Promise of Extracellular Vesicles
por: René, Charlotte A., et al.
Publicado: (2021)

Drugs in Central Nervous System Disorders
por: Perry, Bruce D.
Publicado: (1985)

Molecular Mechanisms of Central Nervous System Axonal Regeneration and Remyelination: A Review
por: Uyeda, Akiko, et al.
Publicado: (2020)

Overexpression of Midkine in Pancreatic Duct Adenocarcinomas Induced by N‐Nitrosobis(2‐oxopropyl)amine in Hamsters and Their Cell Lines
por: Tsutsumi, Masahiro, et al.
Publicado: (2000)

The expression and function of midkine in the vertebrate retina
por: Gramage, E, et al.
Publicado: (2014)

Frequent Expression of Midkine Gene in Esophageal Cancer Suggests a Potential Usage of Its Promoter for Suicide Gene Therapy
por: Miyauchi, Motohiro, et al.
Publicado: (1999)

Progress and Promise of Nur77-based Therapeutics for Central Nervous System Disorders
por: Liu, Lu, et al.
Publicado: (2021)

Midkine: A Novel Prognostic Biomarker for Cancer
por: Jono, Hirofumi, et al.
Publicado: (2010)

The Circulating Midkine in the Newly Diagnosed Celiac Disease: Clinical Implications
por: Emami, Mohammad Hassan, et al.
Publicado: (2021)

Mitotherapy: Unraveling a Promising Treatment for Disorders of the Central Nervous System and Other Systemic Conditions
por: Nascimento-dos-Santos, Gabriel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7k4306o1jnf8sogu8l8jinmf6v