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Meganucleases and Other Tools for Targeted Genome Engineering: Perspectives and Challenges for Gene Therapy
The importance of safer approaches for gene therapy has been underscored by a series of severe adverse events (SAEs) observed in patients involved in clinical trials for Severe Combined Immune Deficiency Disease (SCID) and Chromic Granulomatous Disease (CGD). While a new generation of viral vectors...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Bentham Science Publishers Ltd
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267165/ https://www.ncbi.nlm.nih.gov/pubmed/21182466 http://dx.doi.org/10.2174/156652311794520111 |