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Differential Role of PKC-Induced c-Jun in HTLV-1 LTR Activation by 12-O-Tetradecanoylphorbol-13-acetate in Different Human T-cell Lines

We have previously shown that TPA activates HTLV-1 LTR in Jurkat T-cells by inducing the binding of Sp1-p53 complex to the Sp1 site residing within the Ets responsive region 1 (ERR-1) of the LTR and that this activation is inhibited by PKCalpha and PKCepsilon. However, in H9 T-cells TPA has been not...

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Detalles Bibliográficos
Autores principales:	Abou-Kandil, Ammar, Chamias, Rachel, Huleihel, Mahmoud, Godbey, W. T., Aboud, Mordechai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267723/ https://www.ncbi.nlm.nih.gov/pubmed/22299029 http://dx.doi.org/10.1371/journal.pone.0029934

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