Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture

The stresses encountered during islet isolation and culture may have deleterious effects on beta-cell physiology. However, the biological response of human islet cells to isolation remains poorly characterized. A better understanding of the network of signaling pathways induced by islet isolation an...

Descripción completa

Detalles Bibliográficos
Autores principales: Negi, Sarita, Jetha, Arif, Aikin, Reid, Hasilo, Craig, Sladek, Rob, Paraskevas, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267725/
https://www.ncbi.nlm.nih.gov/pubmed/22299040
http://dx.doi.org/10.1371/journal.pone.0030415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267725/
https://www.ncbi.nlm.nih.gov/pubmed/22299040
http://dx.doi.org/10.1371/journal.pone.0030415

Ejemplares similares