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Inhibition of Wnt/β-Catenin Signaling by a Soluble Collagen-Derived Frizzled Domain Interacting with Wnt3a and the Receptors Frizzled 1 and 8

The Wnt/β-catenin pathway controls cell proliferation, death and differentiation. Several families of extracellular proteins can antagonize Wnt/β-catenin signaling, including the decoy receptors known as secreted frizzled related proteins (SFRPs), which have a cysteine-rich domain (CRD) structurally...

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Detalles Bibliográficos
Autores principales: Hendaoui, Ismaïl, Lavergne, Elise, Lee, Heun-Sik, Hong, Seong Hyun, Kim, Hak-Zoo, Parent, Christelle, Heuzé-Vourc'h, Nathalie, Clément, Bruno, Musso, Orlando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267734/
https://www.ncbi.nlm.nih.gov/pubmed/22303445
http://dx.doi.org/10.1371/journal.pone.0030601