Activation of Wnt Signaling by Chemically Induced Dimerization of LRP5 Disrupts Cellular Homeostasis

Wnt signaling is crucial for a variety of biological processes, including body axis formation, planar polarity, stem cell maintenance and cellular differentiation. Therefore, targeted manipulation of Wnt signaling in vivo would be extremely useful. By applying chemical inducer of dimerization (CID)...

Descripción completa

Detalles Bibliográficos
Autores principales: Shahi, Payam, Park, Dongsu, Pond, Adam C., Seethammagari, Mamatha, Chiou, Shin-Heng, Cho, Kyucheol, Carstens, Julienne L., Decker, William K., McCrea, Pierre D., Ittmann, Michael M., Rosen, Jeffrey M., Spencer, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267738/
https://www.ncbi.nlm.nih.gov/pubmed/22303459
http://dx.doi.org/10.1371/journal.pone.0030814

Ejemplares similares

Ejemplares similares