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A novel mean-centering method for normalizing microRNA expression from high-throughput RT-qPCR data

BACKGROUND: Normalization is critical for accurate gene expression analysis. A significant challenge in the quantitation of gene expression from biofluids samples is the inability to quantify RNA concentration prior to analysis, underscoring the need for robust normalization tools for this sample ty...

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Detalles Bibliográficos
Autores principales: Wylie, Dennis, Shelton, Jeffrey, Choudhary, Ashish, Adai, Alex T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267743/
https://www.ncbi.nlm.nih.gov/pubmed/22188771
http://dx.doi.org/10.1186/1756-0500-4-555