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A novel mean-centering method for normalizing microRNA expression from high-throughput RT-qPCR data
BACKGROUND: Normalization is critical for accurate gene expression analysis. A significant challenge in the quantitation of gene expression from biofluids samples is the inability to quantify RNA concentration prior to analysis, underscoring the need for robust normalization tools for this sample ty...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267743/ https://www.ncbi.nlm.nih.gov/pubmed/22188771 http://dx.doi.org/10.1186/1756-0500-4-555 |