Cargando…
Nox4 Mediates Renal Cell Carcinoma Cell Invasion through Hypoxia-Induced Interleukin 6- and 8- Production
BACKGROUND: Inflammatory cytokines are detected in the plasma of patients with renal cell carcinoma (RCC) and are associated with poor prognosis. However, the primary cell type involved in producing inflammatory cytokines and the biological significance in RCC remain unknown. Inflammation is associa...
Autores principales: | Fitzgerald, John P., Nayak, Bijaya, Shanmugasundaram, Karthigayan, Friedrichs, William, Sudarshan, Sunil, Eid, Assaad A., DeNapoli, Thomas, Parekh, Dipen J., Gorin, Yves, Block, Karen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267761/ https://www.ncbi.nlm.nih.gov/pubmed/22303451 http://dx.doi.org/10.1371/journal.pone.0030712 |
Ejemplares similares
-
Stabilization of HIF-2alpha through redox regulation of mTORC2 activation and initiation of mRNA translation
por: Nayak, Bijaya K., et al.
Publicado: (2012) -
NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance
por: Shanmugasundaram, Karthigayan, et al.
Publicado: (2017) -
PI3K regulation of the SKP-2/p27 axis through mTORC2
por: Shanmugasundaram, Karthigayan, et al.
Publicado: (2012) -
HIF-1 Mediates Renal Fibrosis in OVE26 Type 1 Diabetic Mice
por: Nayak, Bijaya K., et al.
Publicado: (2016) -
Reduced Expression of Fumarate Hydratase in Clear Cell Renal Cancer Mediates HIF-2α Accumulation and Promotes Migration and Invasion
por: Sudarshan, Sunil, et al.
Publicado: (2011)