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SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer
BACKGROUND: The transcription factor SOX2, which is involved in the induction of pluripotent stem cells and contributes to colorectal carcinogenesis, is associated with a poor prognosis in colon cancer (CC). Furthermore, SOX2 is a repressor of the transcriptional activity of β-catenin in vitro. Sinc...
Autores principales: | Neumann, Jens, Bahr, Fiorina, Horst, David, Kriegl, Lydia, Engel, Jutta, Luque, Raquel Mejias, Gerhard, Markus, Kirchner, Thomas, Jung, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3267776/ https://www.ncbi.nlm.nih.gov/pubmed/22168803 http://dx.doi.org/10.1186/1471-2407-11-518 |
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