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Metal Preferences of Zinc-Binding Motif on Metalloproteases

Almost all naturally occurring metalloproteases are monozinc enzymes. The zinc in any number of zinc metalloproteases has been substituted by some other divalent cation. Almost all Co(II)- or Mn(II)-substituted enzymes maintain the catalytic activity of their zinc counterparts. However, in the case...

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Detalles Bibliográficos
Autores principales: Fukasawa, Kayoko M., Hata, Toshiyuki, Ono, Yukio, Hirose, Junzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268031/
https://www.ncbi.nlm.nih.gov/pubmed/22312463
http://dx.doi.org/10.4061/2011/574816