CD4(+) T Cell-derived Novel Peptide Thp5 Induces Interleukin-4 Production in CD4(+) T Cells to Direct T Helper 2 Cell Differentiation

The differentiation of naïve CD4(+) T cells into T helper 2 (Th2) cells requires production of the cytokine IL-4 in the local microenvironment. It is evident that naïve/quiescently activated CD4(+) T cells produce the IL-4 that drives Th2 cell differentiation. Because early production of IL-4 in naï...

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Detalles Bibliográficos
Autores principales: Khan, Mohd Moin, Chatterjee, Samit, Dwivedi, Ved Prakash, Pandey, Nishant Kumar, Singh, Yogesh, Tousif, Sultan, Bhavesh, Neel Sarovar, Van Kaer, Luc, Das, Jyoti, Das, Gobardhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268440/
https://www.ncbi.nlm.nih.gov/pubmed/22130674
http://dx.doi.org/10.1074/jbc.M111.319947

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