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Circulating MicroRNAs as Minimally Invasive Biomarkers for Cancer Theragnosis and Prognosis

Novel cancer biomarker discovery is urgently needed for cancer theragnosis and prognosis, and among the many possible types of samples, blood is regarded to be ideal for this discovery as it can be collected easily in a minimally invasive manner. Results of the past few years have ascertained the qu...

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Autor principal: Cho, William C. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268566/
https://www.ncbi.nlm.nih.gov/pubmed/22303306
http://dx.doi.org/10.3389/fgene.2011.00007
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author Cho, William C. S.
author_facet Cho, William C. S.
author_sort Cho, William C. S.
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description Novel cancer biomarker discovery is urgently needed for cancer theragnosis and prognosis, and among the many possible types of samples, blood is regarded to be ideal for this discovery as it can be collected easily in a minimally invasive manner. Results of the past few years have ascertained the quantification of microRNA (miRNA) as a promising approach for the detection and prognostication of cancer. Indeed, an increasing number of studies have shown that circulating cancer-associated miRNAs are readily measured in plasma or serum and they can robustly discriminate cancer patients from healthy controls, as well as distinguishing between good-prognosis and poor-prognosis patients. Furthermore, recent findings also suggest the potential of circulating miRNAs in the screening, monitoring, and treatment of cancer. This article summarizes the most significant and latest discoveries of original researches on circulating miRNAs involvement in cancer, focusing on the potential of circulating miRNAs as minimally invasive biomarkers for cancer theragnosis and prognosis.
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spelling pubmed-32685662012-02-02 Circulating MicroRNAs as Minimally Invasive Biomarkers for Cancer Theragnosis and Prognosis Cho, William C. S. Front Genet Genetics Novel cancer biomarker discovery is urgently needed for cancer theragnosis and prognosis, and among the many possible types of samples, blood is regarded to be ideal for this discovery as it can be collected easily in a minimally invasive manner. Results of the past few years have ascertained the quantification of microRNA (miRNA) as a promising approach for the detection and prognostication of cancer. Indeed, an increasing number of studies have shown that circulating cancer-associated miRNAs are readily measured in plasma or serum and they can robustly discriminate cancer patients from healthy controls, as well as distinguishing between good-prognosis and poor-prognosis patients. Furthermore, recent findings also suggest the potential of circulating miRNAs in the screening, monitoring, and treatment of cancer. This article summarizes the most significant and latest discoveries of original researches on circulating miRNAs involvement in cancer, focusing on the potential of circulating miRNAs as minimally invasive biomarkers for cancer theragnosis and prognosis. Frontiers Research Foundation 2011-02-28 /pmc/articles/PMC3268566/ /pubmed/22303306 http://dx.doi.org/10.3389/fgene.2011.00007 Text en Copyright © 2011 Cho. http://www.frontiersin.org/licenseagreement This is an open-access article subject to an exclusive license agreement between the authors and Frontiers Media SA, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
spellingShingle Genetics
Cho, William C. S.
Circulating MicroRNAs as Minimally Invasive Biomarkers for Cancer Theragnosis and Prognosis
title Circulating MicroRNAs as Minimally Invasive Biomarkers for Cancer Theragnosis and Prognosis
title_full Circulating MicroRNAs as Minimally Invasive Biomarkers for Cancer Theragnosis and Prognosis
title_fullStr Circulating MicroRNAs as Minimally Invasive Biomarkers for Cancer Theragnosis and Prognosis
title_full_unstemmed Circulating MicroRNAs as Minimally Invasive Biomarkers for Cancer Theragnosis and Prognosis
title_short Circulating MicroRNAs as Minimally Invasive Biomarkers for Cancer Theragnosis and Prognosis
title_sort circulating micrornas as minimally invasive biomarkers for cancer theragnosis and prognosis
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268566/
https://www.ncbi.nlm.nih.gov/pubmed/22303306
http://dx.doi.org/10.3389/fgene.2011.00007
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