Cargando…

Peripheral Blood RNA Expression Profiling in Illicit Methcathinone Users Reveals Effect on Immune System

Methcathinone (ephedrone) is relatively easily accessible for abuse. Its users develop an extrapyramidal syndrome and it is not known if this is caused by methcathinone itself, by side-ingredients (manganese), or both. In the present study we aimed to clarify molecular mechanisms underlying this con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sikk, Katrin, Kõks, Sulev, Soomets, Ursel, Schalkwyk, Leonard C., Fernandes, Cathy, Haldre, Sulev, Aquilonius, Sten-Magnus, Taba, Pille
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268596/ https://www.ncbi.nlm.nih.gov/pubmed/22303338 http://dx.doi.org/10.3389/fgene.2011.00042

Ejemplares similares

Peripheral blood RNA gene expression profiling in patients with bacterial meningitis
por: Lill, Margit, et al.
Publicado: (2013)

Manganese-Induced Parkinsonism due to Ephedrone Abuse
por: Sikk, Katrin, et al.
Publicado: (2011)

Acute effects of methcathinone and manganese in mice: A dose response study
por: Asser, Andres, et al.
Publicado: (2019)

Subacute administration of both methcathinone and manganese causes basal ganglia damage in mice resembling that in methcathinone abusers
por: Asser, Andres, et al.
Publicado: (2019)

Changes in the Peripheral Blood Gene Expression Profile Induced by 3 Months of Valproate Treatment in Patients with Newly Diagnosed Epilepsy
por: Rakitin, Aleksei, et al.
Publicado: (2015)

Effect of Chronic Valproic Acid Treatment on Hepatic Gene Expression Profile in Wfs1 Knockout Mouse
por: Punapart, Marite, et al.
Publicado: (2014)

Dissociation of reward and effort sensitivity in methcathinone‐induced Parkinsonism
por: Chong, Trevor T.‐J., et al.
Publicado: (2017)

Comparison of the Metabolic Syndrome Risk in Valproate-Treated Patients with Epilepsy and the General Population in Estonia
por: Rakitin, Aleksei, et al.
Publicado: (2014)

Serum Amyloid Alpha Is Downregulated in Peripheral Tissues of Parkinson’s Disease Patients
por: Kurvits, Lille, et al.
Publicado: (2019)

Grey matter abnormalities in methcathinone abusers with a Parkinsonian syndrome
por: Juurmaa, Julius, et al.
Publicado: (2016)

Looking beyond the brain to improve the pathogenic understanding of Parkinson’s disease: implications of whole transcriptome profiling of Patients’ skin
por: Planken, Anu, et al.
Publicado: (2017)

Genomics of Wolfram Syndrome 1 (WFS1)
por: Kõks, Sulev
Publicado: (2023)

COL1A1/2 Pathogenic Variants and Phenotype Characteristics in Ukrainian Osteogenesis Imperfecta Patients
por: Zhytnik, Lidiia, et al.
Publicado: (2019)

Detecting Embryo Developmental Potential by Single Blastomere RNA-Seq
por: Nõmm, Monika, et al.
Publicado: (2023)

Smoking-related general and cause-specific mortality in Estonia
por: Kõks, Gea, et al.
Publicado: (2017)

Transcriptional Basis of Psoriasis from Large Scale Gene Expression Studies: The Importance of Moving towards a Precision Medicine Approach
por: Krishnan, Vidya S., et al.
Publicado: (2022)

(123)I-ADAM SPET imaging of serotonin transporter in patients with epilepsy and comorbid depression
por: Liik, Maarika, et al.
Publicado: (2013)

Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones
por: Zhou, Xun, et al.
Publicado: (2020)

Mid-Gestational Gene Expression Profile in Placenta and Link to Pregnancy Complications
por: Uusküla, Liis, et al.
Publicado: (2012)

Genome-Wide Differential Transcription of Long Noncoding RNAs in Psoriatic Skin
por: Stacey, Valerie M., et al.
Publicado: (2023)

RNA‐sequencing of WFS1‐deficient pancreatic islets
por: Ivask, Marilin, et al.
Publicado: (2016)

Analysis of repetitive element expression in the blood and skin of patients with Parkinson’s disease identifies differential expression of satellite elements
por: Billingsley, Kimberley J., et al.
Publicado: (2019)

Analysis of the Expression of Repetitive DNA Elements in Osteosarcoma
por: Ho, Xuan D., et al.
Publicado: (2017)

Manganese Encephalopathy Caused by Homemade Methcathinone (Ephedrone) Prevalence in Poland
por: Habrat, Bogusław, et al.
Publicado: (2021)

Analysis of metabolic effects of menthol on WFS1‐deficient mice
por: Ehrlich, Marite, et al.
Publicado: (2016)

Proteomic dataset of wolframin-deficient mouse heart and skeletal muscles
por: Eimre, Margus, et al.
Publicado: (2018)

Recent Insights into the Role of Unfolded Protein Response in ER Stress in Health and Disease
por: Lindholm, Dan, et al.
Publicado: (2017)

Creutzfeldt-Jakob Disease Presenting as Nonconvulsive Status Epilepticus
por: Rakitin, Aleksei, et al.
Publicado: (2018)

Development of new levodopa treatment strategies in Parkinson’s disease—from bedside to bench to bedside
por: Aquilonius, Sten-Magnus, et al.
Publicado: (2017)

Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice
por: Tein, Karin, et al.
Publicado: (2015)

Aneurysmal subarachnoid haemorrhage: effect of CRHR1 genotype on fatigue and depression
por: Vetkas, Artur, et al.
Publicado: (2020)

RNA sequencing analysis reveals increased expression of interferon signaling genes and dysregulation of bone metabolism affecting pathways in the whole blood of patients with osteogenesis imperfecta
por: Zhytnik, Lidiia, et al.
Publicado: (2020)

Aneurysmal subarachnoid haemorrhage: Effect of CRHR1 genotype on mental health-related quality of life
por: Vetkas, Artur, et al.
Publicado: (2020)

Identification of an optimal method for extracting RNA from human skin biopsy, using domestic pig as a model system
por: Reimann, Ene, et al.
Publicado: (2019)

Whole exome sequencing of a single osteosarcoma case—integrative analysis with whole transcriptome RNA-seq data
por: Reimann, Ene, et al.
Publicado: (2014)

An Increased Burden of Highly Active Retrotransposition Competent L1s Is Associated with Parkinson’s Disease Risk and Progression in the PPMI Cohort
por: Pfaff, Abigail L., et al.
Publicado: (2020)

Transcript Variants of Genes Involved in Neurodegeneration Are Differentially Regulated by the APOE and MAPT Haplotypes
por: Koks, Sulev, et al.
Publicado: (2021)

Expression Quantitative Trait Loci (eQTLs) Associated with Retrotransposons Demonstrate their Modulatory Effect on the Transcriptome
por: Koks, Sulev, et al.
Publicado: (2021)

Reference SVA insertion polymorphisms are associated with Parkinson’s Disease progression and differential gene expression
por: Pfaff, Abigail L., et al.
Publicado: (2021)

Locus specific reduction of L1 expression in the cortices of individuals with amyotrophic lateral sclerosis
por: Pfaff, Abigail L., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_eikapj7apc4ma6dagarftpvqst