Perinatal Exogenous Nitric Oxide in Fawn-Hooded Hypertensive Rats Reduces Renal Ribosomal Biogenesis in Early Life

Nitric oxide (NO) is known to depress ribosome biogenesis in vitro. In this study we analyzed the influence of exogenous NO on ribosome biogenesis in vivo using a proven antihypertensive model of perinatal NO administration in genetically hypertensive rats. Fawn-hooded hypertensive rat (FHH) dams we...

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Detalles Bibliográficos
Autores principales: Wesseling, Sebastiaan, Essers, Paul B., Koeners, Maarten P., Pereboom, Tamara C., Braam, Branko, van Faassen, Ernst E., MacInnes, Alyson W., Joles, Jaap A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268605/
https://www.ncbi.nlm.nih.gov/pubmed/22303348
http://dx.doi.org/10.3389/fgene.2011.00052

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