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A Narrow Quantitative Trait Locus in C. elegans Coordinately Affects Longevity, Thermotolerance, and Resistance to Paraquat

By linkage mapping of quantitative trait loci, we previously identified at least 11 natural genetic variants that significantly modulate Caenorhabditis elegans life-span (LS), many of which would have eluded discovery by knock-down or mutation screens. A region on chromosome IV between markers stP13...

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Detalles Bibliográficos
Autores principales: Vertino, Anthony, Ayyadevara, Srinivas, Thaden, John J., Reis, Robert J. Shmookler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268616/
https://www.ncbi.nlm.nih.gov/pubmed/22303358
http://dx.doi.org/10.3389/fgene.2011.00063