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A Comparison of Association Methods for Cytotoxicity Mapping in Pharmacogenomics

Cytotoxicity assays of immortalized lymphoblastoid cell lines (LCLs) represent a promising new in vitro approach in pharmacogenomics research. However, previous studies employing LCLs in gene mapping have used simple association methods, which may not adequately capture the true differences in non-l...

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Detalles Bibliográficos
Autores principales: Brown, Chad, Havener, Tammy M., Everitt, Lorraine, McLeod, Howard, Motsinger-Reif, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268638/
https://www.ncbi.nlm.nih.gov/pubmed/22303380
http://dx.doi.org/10.3389/fgene.2011.00086